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Managing Chronic Pain and Opioid Use Disorder with Dr. Jessie Merlin

The Curbsiders Internal Medicine PodcastJune 16, 20251h 21min1,650 views
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Understanding Chronic Pain and Opioid Use Disorder

  • 🎯 Chronic pain is defined as pain lasting longer than 3 months beyond normal healing, impacting 20% of the US population, with 6% experiencing high-impact chronic pain.
  • 🀝 The reciprocal model of pain and addiction highlights how pain can drive substance use, and addiction can exacerbate pain, creating a complex loop.
  • πŸ’‘ Clinicians often mistakenly view pain and addiction as separate issues, when in reality, their intersection is critical for effective management.
  • ⚠️ Trauma, such as physical injury, is a significant factor that can be closely related to chronic pain, addiction, and PTSD.

Clinical Misconceptions and Assessment

  • 🧠 A common misconception is that patients cannot have both chronic pain and opioid use disorder; the reality is they frequently co-occur and interact.
  • πŸ—£οΈ Clinicians should actively ask patients about their pain and substance use, as patients may be reluctant to disclose pain due to fear of being labeled as "drug-seeking."
  • πŸ‘‚ Patient priorities are paramount; pain often ranks higher than substance use disorder for patients, making pain a potential entry point for treatment.
  • πŸ—ΊοΈ A thorough history and physical exam should include functional assessments, such as the PEG scale (Pain, Enjoyment of life, General activity), to gauge impact.
  • 🀝 Prior negative experiences with the healthcare system can lead to patient mistrust; empathy, validation, and setting clear expectations are crucial for building rapport.

Treatment Modalities and Medications

  • πŸ’Š Buprenorphine, an FDA-approved medication for opioid use disorder, is also effective for chronic pain, comparable to other opioids, though optimal dosing for pain is still being researched.
  • πŸ₯ Methadone is another option for opioid use disorder and pain, but its use for addiction is restricted to licensed opioid treatment programs, creating a parallel system of care.
  • 🚫 Naltrexone is less effective for opioid use disorder retention compared to buprenorphine and methadone, despite some studies showing benefit for pain in certain populations.
  • πŸ”¬ Behavioral interventions, such as Cognitive Behavioral Therapy (CBT) and pain self-management programs, are highly effective and safe for chronic pain management.
  • 🧘 Mindfulness-based interventions and movement-based approaches like yoga and Tai Chi are also evidence-based options for pain management.

Navigating Opioid Prescribing and Flares

  • βš–οΈ When considering opioid prescribing, the decision must weigh benefits against risks, especially for patients with a history of opioid use disorder.
  • ⚠️ For patients with a prognosis of greater than one year, prescribing full agonist opioids for chronic pain with comorbid opioid use disorder is generally less appropriate.
  • πŸ“ˆ Opioids are not strongly evidence-based for chronic pain; their effectiveness is comparable to NSAIDs, and genetic factors influence individual responses.
  • πŸš€ Buprenorphine is increasingly recommended as a first-line opioid for chronic pain, even in patients without a history of opioid use disorder, due to its safety profile and fewer side effects.
  • ❄️ Acute flares of chronic pain should be managed cautiously, distinguishing them from new, unrelated acute pain to avoid inappropriate long-term opioid use.

Best Practices and Documentation

  • 🧩 Multidisciplinary pain clinics offer the most effective approach by combining various treatment strategies, though integrating these components into primary care is challenging.
  • πŸ“š Resources like opioid-algorithms.edu and books such as "Managing Chronic Pain Before It Manages You" can support clinicians and patients.
  • πŸ“ Accurate and non-judgmental documentation of patient behaviors, such as missed appointments or taking more medication than prescribed, is crucial for informing future care decisions.
  • 🀝 Clinicians should aim to treat both chronic pain and opioid use disorder, recognizing that they possess or can develop the necessary tools to manage these complex conditions effectively.
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What’s Discussed

Chronic PainOpioid Use DisorderAddiction MedicinePain ManagementBuprenorphineMethadoneCognitive Behavioral TherapyBehavioral InterventionsOpioid PrescribingPain FlaresNaltrexonePrimary CareSubstance Use Disorder
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